Docking Studies of Green Tea Flavonoids as Insulin Mimetics

Diabetes Mellitus is a metabolism disorder where glucose, principal source of energy cannot enter the cells due to deficiency of insulin. In the present study, insilico approach was used to asses the use of natural green tea flavonoids as potential agents that could act as insulin receptor activators and reduce the harmful effects of diabetes. Docking studies of green tea flavanoids were carried out using Auto Dock 4.0 and Argus lab 4.0.1. Analysis of the results of both the docking softwares suggested that epicatechin can act as a potent insulin receptor activator.