A novel non-enzymatic glucose sensor based on Cu nanoparticle modified graphene sheets electrode

[Display omitted] ► We electrodeposited Cu nanoparticles on graphene sheets. ► The obtained Cu-graphene sheets nanocomposite is a good catalyst for the oxidation of glucose. ► Wide linear range, low detection limit as well as quick response for glucose. ► Easy fabrication, low cost, good reproducibi...

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Veröffentlicht in:Analytica chimica acta 2012-01, Vol.709, p.47-53
Hauptverfasser: Luo, Jing, Jiang, Sisi, Zhang, Hongyan, Jiang, Jinqiang, Liu, Xiaoya
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Jiang, Sisi
Zhang, Hongyan
Jiang, Jinqiang
Liu, Xiaoya
description [Display omitted] ► We electrodeposited Cu nanoparticles on graphene sheets. ► The obtained Cu-graphene sheets nanocomposite is a good catalyst for the oxidation of glucose. ► Wide linear range, low detection limit as well as quick response for glucose. ► Easy fabrication, low cost, good reproducibility and perfect specificity to glucose in the presence of interferents. A novel, stable and sensitive non-enzymatic glucose sensor was developed by potentiostatically electrodepositing metallic Cu nanoparticles on graphene sheets. The electrochemical performance of the Cu-graphene sheets electrode for detection of glucose was investigated by cyclic voltammetry and chronamperometry. The Cu-graphene sheets electrode displayed a synergistic effect of copper nanoparticles and graphene sheets towards the oxidation of glucose in alkaline solution, showing higher oxidation current and negative shift in peak potential. At detection potential of 500 mV, the Cu-graphene electrode sensor presented a wide linear range up to 4.5 mM glucose with a detection limit of 0.5 μM (signal/noise = 3). In addition, the sensor responds very quickly (
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A novel, stable and sensitive non-enzymatic glucose sensor was developed by potentiostatically electrodepositing metallic Cu nanoparticles on graphene sheets. The electrochemical performance of the Cu-graphene sheets electrode for detection of glucose was investigated by cyclic voltammetry and chronamperometry. The Cu-graphene sheets electrode displayed a synergistic effect of copper nanoparticles and graphene sheets towards the oxidation of glucose in alkaline solution, showing higher oxidation current and negative shift in peak potential. At detection potential of 500 mV, the Cu-graphene electrode sensor presented a wide linear range up to 4.5 mM glucose with a detection limit of 0.5 μM (signal/noise = 3). In addition, the sensor responds very quickly (&lt;2 s) with addition of glucose. Furthermore, the Cu-graphene sheets electrode exhibits high stability and selectivity to glucose, and the poisoning by chloride ion as well as interference from the oxidation of common interfering species (ascorbic, dopamine, uric acid and carbohydrate) are effectively avoided. 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A novel, stable and sensitive non-enzymatic glucose sensor was developed by potentiostatically electrodepositing metallic Cu nanoparticles on graphene sheets. The electrochemical performance of the Cu-graphene sheets electrode for detection of glucose was investigated by cyclic voltammetry and chronamperometry. The Cu-graphene sheets electrode displayed a synergistic effect of copper nanoparticles and graphene sheets towards the oxidation of glucose in alkaline solution, showing higher oxidation current and negative shift in peak potential. At detection potential of 500 mV, the Cu-graphene electrode sensor presented a wide linear range up to 4.5 mM glucose with a detection limit of 0.5 μM (signal/noise = 3). In addition, the sensor responds very quickly (&lt;2 s) with addition of glucose. Furthermore, the Cu-graphene sheets electrode exhibits high stability and selectivity to glucose, and the poisoning by chloride ion as well as interference from the oxidation of common interfering species (ascorbic, dopamine, uric acid and carbohydrate) are effectively avoided. 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A novel, stable and sensitive non-enzymatic glucose sensor was developed by potentiostatically electrodepositing metallic Cu nanoparticles on graphene sheets. The electrochemical performance of the Cu-graphene sheets electrode for detection of glucose was investigated by cyclic voltammetry and chronamperometry. The Cu-graphene sheets electrode displayed a synergistic effect of copper nanoparticles and graphene sheets towards the oxidation of glucose in alkaline solution, showing higher oxidation current and negative shift in peak potential. At detection potential of 500 mV, the Cu-graphene electrode sensor presented a wide linear range up to 4.5 mM glucose with a detection limit of 0.5 μM (signal/noise = 3). In addition, the sensor responds very quickly (&lt;2 s) with addition of glucose. Furthermore, the Cu-graphene sheets electrode exhibits high stability and selectivity to glucose, and the poisoning by chloride ion as well as interference from the oxidation of common interfering species (ascorbic, dopamine, uric acid and carbohydrate) are effectively avoided. The Cu-graphene sheets electrode allows highly selective and sensitive, stable and fast amperometric sensing of glucose, which is promising for the development of non-enzymatic glucose sensor.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>22122930</pmid><doi>10.1016/j.aca.2011.10.025</doi><tpages>7</tpages></addata></record>
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subjects Analytical chemistry
Catalysis
Chemistry
Copper
Copper - chemistry
Copper nanoparticles
Electrochemical methods
Electrochemical Techniques
Electrodeposition
Electrodes
Electroplating
Exact sciences and technology
General, instrumentation
Glucose
Glucose - analysis
Graphene
Graphene sheets
Graphite - chemistry
Metal Nanoparticles - chemistry
Nanoparticles
Nanostructure
Non-enzymatic sensor
Oxidation
Oxidation-Reduction
Oxides - chemistry
Sensors
title A novel non-enzymatic glucose sensor based on Cu nanoparticle modified graphene sheets electrode
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