A novel non-enzymatic glucose sensor based on Cu nanoparticle modified graphene sheets electrode

[Display omitted] ► We electrodeposited Cu nanoparticles on graphene sheets. ► The obtained Cu-graphene sheets nanocomposite is a good catalyst for the oxidation of glucose. ► Wide linear range, low detection limit as well as quick response for glucose. ► Easy fabrication, low cost, good reproducibility and perfect specificity to glucose in the presence of interferents. A novel, stable and sensitive non-enzymatic glucose sensor was developed by potentiostatically electrodepositing metallic Cu nanoparticles on graphene sheets. The electrochemical performance of the Cu-graphene sheets electrode for detection of glucose was investigated by cyclic voltammetry and chronamperometry. The Cu-graphene sheets electrode displayed a synergistic effect of copper nanoparticles and graphene sheets towards the oxidation of glucose in alkaline solution, showing higher oxidation current and negative shift in peak potential. At detection potential of 500 mV, the Cu-graphene electrode sensor presented a wide linear range up to 4.5 mM glucose with a detection limit of 0.5 μM (signal/noise = 3). In addition, the sensor responds very quickly (