Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice
Highlights ► An original and innovative research on Th2-biased immune response and pathogenic mechanisms of schistosomiasis is present. ► Areas in immunology that may benefit from immune-regulatory effects induced by the helminth–schistosome are also discussed.
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Veröffentlicht in: | Immunology letters 2012-05, Vol.144 (1), p.60-66 |
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container_title | Immunology letters |
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creator | Qi, Yao Song, Xiao-rong Shen, Ji-long Xu, Yuan-hong Shen, Qian Luo, Qing-li Zhong, Zheng-rong Wang, Wei Chu, De-yong Song, Wen-jian |
description | Highlights ► An original and innovative research on Th2-biased immune response and pathogenic mechanisms of schistosomiasis is present. ► Areas in immunology that may benefit from immune-regulatory effects induced by the helminth–schistosome are also discussed. |
doi_str_mv | 10.1016/j.imlet.2012.03.007 |
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All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c480t-fb871f8aac36aed736bf6df2fb010723bdc17ac5dffecde4882b0ff68154dd813</citedby><cites>FETCH-LOGICAL-c480t-fb871f8aac36aed736bf6df2fb010723bdc17ac5dffecde4882b0ff68154dd813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.imlet.2012.03.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22469568$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Qi, Yao</creatorcontrib><creatorcontrib>Song, Xiao-rong</creatorcontrib><creatorcontrib>Shen, Ji-long</creatorcontrib><creatorcontrib>Xu, Yuan-hong</creatorcontrib><creatorcontrib>Shen, Qian</creatorcontrib><creatorcontrib>Luo, Qing-li</creatorcontrib><creatorcontrib>Zhong, Zheng-rong</creatorcontrib><creatorcontrib>Wang, Wei</creatorcontrib><creatorcontrib>Chu, De-yong</creatorcontrib><creatorcontrib>Song, Wen-jian</creatorcontrib><title>Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice</title><title>Immunology letters</title><addtitle>Immunol Lett</addtitle><description>Highlights ► An original and innovative research on Th2-biased immune response and pathogenic mechanisms of schistosomiasis is present. ► Areas in immunology that may benefit from immune-regulatory effects induced by the helminth–schistosome are also discussed.</description><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Apoptosis</subject><subject>Cell Differentiation</subject><subject>Female</subject><subject>Galectin-9</subject><subject>Galectins - genetics</subject><subject>Galectins - metabolism</subject><subject>Hepatitis A Virus Cellular Receptor 2</subject><subject>Membrane Proteins - genetics</subject><subject>Membrane Proteins - metabolism</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Receptors, Virus - genetics</subject><subject>Receptors, Virus - metabolism</subject><subject>Schistosoma japonicum - immunology</subject><subject>Schistosoma japonicum - pathogenicity</subject><subject>Schistosomiasis</subject><subject>Schistosomiasis japonica - immunology</subject><subject>Schistosomiasis japonica - parasitology</subject><subject>Schistosomiasis japonica - physiopathology</subject><subject>T cell immunoglobulin domain and mucin domain</subject><subject>T-Lymphocytes - cytology</subject><subject>T-Lymphocytes - immunology</subject><subject>T-Lymphocytes - physiology</subject><subject>Th2 Cells - immunology</subject><subject>Th2 Cells - metabolism</subject><subject>Th2-biased response</subject><subject>Up-Regulation</subject><issn>0165-2478</issn><issn>1879-0542</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtv1TAQRi1ERS-FX4CEsmTjMLbz8F2AhCpeUiUWvV1bjj3udcgLO2l1F_3vOKSwYNOVpfH5ZjRnCHnDIGfAqvdt7vsO55wD4zmIHKB-RnZM1nsKZcGfk12iSsqLWp6TlzG2AKwUhXhBzjkvqn1ZyR15OPie8myZaMDbpdOzH4dMDza71R2a2Q90T1dEZJOej_f6lOlUvds4P2SHI6eN1xFtFjBO4xBxLV-bo4_zGMdeZ61OZW-WPn24teeW7L3BV-TM6S7i68f3gtx8-Xy4_Eavfnz9fvnpippCwkxdI2vmpNZGVBptLarGVdZx1wCDmovGGlZrU1qX-lsspOQNOFdJVhbWSiYuyLut7xTGXwvGWfU-Guw6PeC4RJV8QrFPVkRCxYaaMMYY0Kkp-F6HU4JWrlKt-uNdrd4VCJW8p9TbxwFL06P9l_krOgEfNgDTmnceg4rG42DQ-pCcKDv6JwZ8_C9vOp-s6u4nnjC24xKGZFAxFVNGXa-nXy_POADIshS_AVTMq9k</recordid><startdate>20120530</startdate><enddate>20120530</enddate><creator>Qi, Yao</creator><creator>Song, Xiao-rong</creator><creator>Shen, Ji-long</creator><creator>Xu, Yuan-hong</creator><creator>Shen, Qian</creator><creator>Luo, Qing-li</creator><creator>Zhong, Zheng-rong</creator><creator>Wang, Wei</creator><creator>Chu, De-yong</creator><creator>Song, Wen-jian</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120530</creationdate><title>Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice</title><author>Qi, Yao ; Song, Xiao-rong ; Shen, Ji-long ; Xu, Yuan-hong ; Shen, Qian ; Luo, Qing-li ; Zhong, Zheng-rong ; Wang, Wei ; Chu, De-yong ; Song, Wen-jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-fb871f8aac36aed736bf6df2fb010723bdc17ac5dffecde4882b0ff68154dd813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Apoptosis</topic><topic>Cell Differentiation</topic><topic>Female</topic><topic>Galectin-9</topic><topic>Galectins - genetics</topic><topic>Galectins - metabolism</topic><topic>Hepatitis A Virus Cellular Receptor 2</topic><topic>Membrane Proteins - genetics</topic><topic>Membrane Proteins - metabolism</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Receptors, Virus - genetics</topic><topic>Receptors, Virus - metabolism</topic><topic>Schistosoma japonicum - immunology</topic><topic>Schistosoma japonicum - pathogenicity</topic><topic>Schistosomiasis</topic><topic>Schistosomiasis japonica - immunology</topic><topic>Schistosomiasis japonica - parasitology</topic><topic>Schistosomiasis japonica - physiopathology</topic><topic>T cell immunoglobulin domain and mucin domain</topic><topic>T-Lymphocytes - cytology</topic><topic>T-Lymphocytes - immunology</topic><topic>T-Lymphocytes - physiology</topic><topic>Th2 Cells - immunology</topic><topic>Th2 Cells - metabolism</topic><topic>Th2-biased response</topic><topic>Up-Regulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Qi, Yao</creatorcontrib><creatorcontrib>Song, Xiao-rong</creatorcontrib><creatorcontrib>Shen, Ji-long</creatorcontrib><creatorcontrib>Xu, Yuan-hong</creatorcontrib><creatorcontrib>Shen, Qian</creatorcontrib><creatorcontrib>Luo, Qing-li</creatorcontrib><creatorcontrib>Zhong, Zheng-rong</creatorcontrib><creatorcontrib>Wang, Wei</creatorcontrib><creatorcontrib>Chu, De-yong</creatorcontrib><creatorcontrib>Song, Wen-jian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Immunology letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Qi, Yao</au><au>Song, Xiao-rong</au><au>Shen, Ji-long</au><au>Xu, Yuan-hong</au><au>Shen, Qian</au><au>Luo, Qing-li</au><au>Zhong, Zheng-rong</au><au>Wang, Wei</au><au>Chu, De-yong</au><au>Song, Wen-jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice</atitle><jtitle>Immunology letters</jtitle><addtitle>Immunol Lett</addtitle><date>2012-05-30</date><risdate>2012</risdate><volume>144</volume><issue>1</issue><spage>60</spage><epage>66</epage><pages>60-66</pages><issn>0165-2478</issn><eissn>1879-0542</eissn><abstract>Highlights ► An original and innovative research on Th2-biased immune response and pathogenic mechanisms of schistosomiasis is present. ► Areas in immunology that may benefit from immune-regulatory effects induced by the helminth–schistosome are also discussed.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>22469568</pmid><doi>10.1016/j.imlet.2012.03.007</doi><tpages>7</tpages></addata></record> |
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subjects | Allergy and Immunology Animals Apoptosis Cell Differentiation Female Galectin-9 Galectins - genetics Galectins - metabolism Hepatitis A Virus Cellular Receptor 2 Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Inbred BALB C Receptors, Virus - genetics Receptors, Virus - metabolism Schistosoma japonicum - immunology Schistosoma japonicum - pathogenicity Schistosomiasis Schistosomiasis japonica - immunology Schistosomiasis japonica - parasitology Schistosomiasis japonica - physiopathology T cell immunoglobulin domain and mucin domain T-Lymphocytes - cytology T-Lymphocytes - immunology T-Lymphocytes - physiology Th2 Cells - immunology Th2 Cells - metabolism Th2-biased response Up-Regulation |
title | Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice |
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