Reduced-Intensity Allogeneic Stem Cell Transplantation in Children and Young Adults with Ultrahigh-Risk Pediatric Sarcomas

Reduced-Intensity Allogeneic Stem Cell Transplantation in Children and Young Adults with Ultrahigh-Risk Pediatric Sarcomas

Some subsets of pediatric sarcoma patients have very poor survival rates. We sought to determine the feasibility and efficacy of allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric sarcoma populations with

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Bibliographische Detailangaben
Veröffentlicht in:Biology of blood and marrow transplantation 2012-05, Vol.18 (5), p.698-707
Hauptverfasser: Baird, Kristin, Fry, Terry J, Steinberg, Seth M, Bishop, Michael R, Fowler, Daniel H, Delbrook, Cynthia P, Humphrey, Jennifer L, Rager, Alison, Richards, Kelly, Wayne, Alan S, Mackall, Crystal L
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age Factors
Allogeneic stem cell transplantation
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - therapeutic use
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Child
Cohort Studies
Female
Graft Survival - immunology
Hematology, Oncology and Palliative Medicine
Hematopoietic Stem Cell Transplantation - methods
Humans
Kaplan-Meier Estimate
Male
Pediatric soft tissue sarcoma
Reduced-intensity transplantation
Remission Induction
Risk
Sarcoma - immunology
Sarcoma - mortality
Sarcoma - therapy
Solid tumor
Transplantation Conditioning
Transplantation, Homologous
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Beschreibung
Zusammenfassung:Some subsets of pediatric sarcoma patients have very poor survival rates. We sought to determine the feasibility and efficacy of allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric sarcoma populations with
ISSN:1083-8791
1523-6536
DOI:10.1016/j.bbmt.2011.08.020