Symptomatic Low-Grade Carotid Stenosis With Intraplaque Hemorrhage and Expansive Arterial Remodeling Is Associated With a High Relapse Rate Refractory to Medical Treatment

Symptomatic Low-Grade Carotid Stenosis With Intraplaque Hemorrhage and Expansive Arterial Remodeling Is Associated With a High Relapse Rate Refractory to Medical Treatment

Abstract BACKGROUND: Carotid plaque characteristics influence future risk of stroke considerably. However, the severity of stenosis does not accurately reflect plaque burden in patients with expansive arterial remodeling. OBJECTIVE: To determine the therapeutic outcome of symptomatic carotid low-gra...

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Veröffentlicht in:Neurosurgery 2012-05, Vol.70 (5), p.1143-1151
Hauptverfasser: Yoshida, Kazumichi, Sadamasa, Nobutake, Narumi, Osamu, Chin, Masaki, Yamagata, Sen, Miyamoto, Susumu
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Atherosclerosis
Biological and medical sciences
Carotid Arteries - pathology
Carotid Arteries - surgery
Carotid Stenosis - diagnosis
Carotid Stenosis - therapy
Cerebral Hemorrhage - diagnosis
Cerebral Hemorrhage - therapy
Female
Humans
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medical sciences
Medical treatment
Neurosurgery
Recurrence
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Stroke
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Treatment Failure
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Zusammenfassung:Abstract BACKGROUND: Carotid plaque characteristics influence future risk of stroke considerably. However, the severity of stenosis does not accurately reflect plaque burden in patients with expansive arterial remodeling. OBJECTIVE: To determine the therapeutic outcome of symptomatic carotid low-grade stenosis with vulnerable plaque based on magnetic resonance imaging (MRI) characterization. METHODS: We studied 25 (male, n = 23; age, 74.2 ± 5.6 years) of 29 consecutive patients with symptomatic carotid low-grade stenosis (
ISSN:0148-396X
1524-4040
DOI:10.1227/NEU.0b013e31823fe50b