Extrathymically generated regulatory T cells control mucosal T^sub H^2 inflammation
Two recent studies established a role for TGFb signalling in tTreg cell differentiation in neonates9,10. [...] to exclude the possibility that CNS1 deficiency adversely affects generation of Foxp31 T cells in the neonatal thymus, we examined the Foxp31 Treg cell population in heterozygous female CNS...
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| Veröffentlicht in: | Nature (London) 2012-02, Vol.482 (7385), p.395 |
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| creator | Josefowicz, Steven Z Niec, Rachel E Kim, Hye Young Treuting, Piper Chinen, Takatoshi Zheng, Ye Umetsu, Dale T Rudensky, Alexander Y |
| description | Two recent studies established a role for TGFb signalling in tTreg cell differentiation in neonates9,10. [...] to exclude the possibility that CNS1 deficiency adversely affects generation of Foxp31 T cells in the neonatal thymus, we examined the Foxp31 Treg cell population in heterozygous female CNS1WT/2 mice. |
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| ispartof | Nature (London), 2012-02, Vol.482 (7385), p.395 |
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| language | eng |
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| source | SpringerLink Journals; Nature |
| subjects | Animals Asthma Binding sites Cell differentiation Homeostasis Lungs Lymphocytes Proteins Rodents |
| title | Extrathymically generated regulatory T cells control mucosal T^sub H^2 inflammation |
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