High Dose trans-10,cis-12 CLA Increases Lean Body Mass in Hamsters, but Elevates Levels of Plasma Lipids and Liver Enzyme Biomarkers

The current study examined the efficacy of graded doses of c 9, t 11 and t 10, c 12 CLA isomers on body composition, energy expenditure, hepatic and serum lipid liver biomarkers in hamsters. Animals ( n  = 105) were randomized to seven treatments (control, 1, 2, 3% of c 9, t 11; 1, 2, 3% of t 10, c...

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Veröffentlicht in:Lipids 2012-01, Vol.47 (1), p.39-46
Hauptverfasser: Liu, Xiaoran, Joseph, Shama V., Wakefield, Andrew P., Aukema, Harold M., Jones, Peter J. H.
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Sprache:eng
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Zusammenfassung:The current study examined the efficacy of graded doses of c 9, t 11 and t 10, c 12 CLA isomers on body composition, energy expenditure, hepatic and serum lipid liver biomarkers in hamsters. Animals ( n  = 105) were randomized to seven treatments (control, 1, 2, 3% of c 9, t 11; 1, 2, 3% of t 10, c 12) for 28 days. After 28 days treatment, 1–3% of t 10, c 12 lowered ( p  
ISSN:0024-4201
1558-9307
DOI:10.1007/s11745-011-3616-3