Persistence of TEM-52/TEM-92 and SHV-12 Extended-Spectrum [beta]-Lactamases in Clinical Isolates of Enterobacteriaceae in Italy

Persistence of TEM-52/TEM-92 and SHV-12 Extended-Spectrum [beta]-Lactamases in Clinical Isolates of Enterobacteriaceae in Italy

Extended-spectrum β-lactamases (ESBLs) belonging to the TEM and SHV families were investigated in 583 ESBL-producing Enterobacteriaceae collected at the clinical microbiology laboratories of 11 teaching Italian hospitals. By molecular analysis TEM-type and SHV-type ESBLs were confirmed on 154 and 74...

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Veröffentlicht in:Microbial drug resistance (Larchmont, N.Y.) N.Y.), 2011-12, Vol.17 (4), p.521
Hauptverfasser: Perilli, Mariagrazia, Segatore, Bernardetta, Mugnaioli, Claudia, Celenza, Giuseppe, Rossolini, Gian Maria, Stefani, Stefania, Luzzaro, Francesco, Pini, Beatrice, Amicosante, Gianfranco
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Drug resistance
Enzymes
Hospitals
Microbiology
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Zusammenfassung:Extended-spectrum β-lactamases (ESBLs) belonging to the TEM and SHV families were investigated in 583 ESBL-producing Enterobacteriaceae collected at the clinical microbiology laboratories of 11 teaching Italian hospitals. By molecular analysis TEM-type and SHV-type ESBLs were confirmed on 154 and 74 isolates, respectively. High variability was found among TEM-types β-lactamases with the following variants: TEM-5, TEM-6, TEM-12, TEM-15, TEM-24, TEM-26, TEM-29, TEM-52, TEM-92, TEM-134, and TEM-149. Among SHV variants, SHV-2a, SHV-5, SHV-12, and SHV-28 have been detected. The most widespread variants are TEM-52/92 and SHV-12. [PUBLICATION ABSTRACT]
ISSN:1076-6294
1931-8448
DOI:10.1089/mdr.2011.0059