Decreased virulence of a uropathogenic Escherichia coli pst mutant is attributed to the repression of Type 1 fimbriae

Decreased virulence of a uropathogenic Escherichia coli pst mutant is attributed to the repression of Type 1 fimbriae

Since the Pho regulon is controlled by the TCRS PhoBR, molecules inducing the expression of the Pho regulon through inactivation of Pst or activation of PhoBR could potentially impair UPEC virulence by inhibiting colonization and the infection cycle, which is dependent on expression of type 1 fimbri...

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Veröffentlicht in:BMC proceedings 2011-01, Vol.5 (S1), p.P93, Article P93
Hauptverfasser: Crépin, S, Houle, S, Harel, J, Dozois, CM
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Bladder
E coli
Infections
Meetings
Urogenital system
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Zusammenfassung:Since the Pho regulon is controlled by the TCRS PhoBR, molecules inducing the expression of the Pho regulon through inactivation of Pst or activation of PhoBR could potentially impair UPEC virulence by inhibiting colonization and the infection cycle, which is dependent on expression of type 1 fimbrial adhesins.
ISSN:1753-6561
1753-6561
DOI:10.1186/1753-6561-5-S1-P93