Chemical Cardiomyopathies: The Negative Effects of Medications and Nonprescribed Drugs on the Heart

Abstract The heart is a target of injury for many chemical compounds, both medically prescribed and not medically prescribed. Pathophysiologic mechanisms underlying the development of chemical-induced cardiomyopathies vary depending on the inciting agent, including direct toxic effects, neurohormona...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of medicine 2011-06, Vol.124 (6), p.480-488
1. Verfasser:	Figueredo, Vincent M., MD, FACC, FAHA, FASE
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Amphetamine Amphetamine - adverse effects Anabolic Agents - adverse effects Anabolic steroid Anthracycline Anthracyclines - adverse effects Antineoplastic Agents - adverse effects Biological and medical sciences Cardiology. Vascular system Cardiomyopathies - chemically induced Cardiomyopathies - mortality Cardiomyopathies - physiopathology Cardiomyopathy Chemical compounds Chloroquine Chloroquine - adverse effects Clozapine Clozapine - adverse effects Cobalt Cocaine Cocaine - adverse effects Doxorubicin Doxorubicin - adverse effects Ecstasy Ephedra Ephedra - adverse effects Ethanol - adverse effects General aspects Heart Heart - drug effects Heart - physiopathology Humans Internal Medicine Ma huang Medical sciences Medical treatment Methylenedioxymethamphetamine Methylphenidate Methylphenidate - adverse effects Myocarditis. Cardiomyopathies Nonprescription drugs Nonprescription Drugs - adverse effects Prescription Drugs - adverse effects Side effects Testosterone - adverse effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abstract The heart is a target of injury for many chemical compounds, both medically prescribed and not medically prescribed. Pathophysiologic mechanisms underlying the development of chemical-induced cardiomyopathies vary depending on the inciting agent, including direct toxic effects, neurohormonal activation, altered calcium homeostasis, and oxidative stress. Numerous chemicals and drugs are implicated in cardiomyopathy. This article discusses examples of medication and nonprescribed drug-induced cardiomyopathies and reviews their pathophysiologic mechanisms.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/j.amjmed.2010.11.031