Sacroiliitis and severe disability due to isotretinoin therapy

We report a case of acute sacroiliitis with severe disability after only 3 weeks of isotretinoin therapy with graduate reduction of pain, limitation and muscle incompetence after discontinuation of the drug and ACTH-depo injection and Ethodolac therapy. Naranjo probability scale indicated a probable...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Rheumatology international 2010-05, Vol.30 (7), p.985-986
Hauptverfasser:	Rozin, Alexander P., Kagna, Olga, Shiller, Yizhak
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne Vulgaris - drug therapy Adrenocorticotropic Hormone - therapeutic use Adult Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthralgia - chemically induced Arthralgia - pathology Arthralgia - physiopathology Arthritis - chemically induced Arthritis - pathology Arthritis - physiopathology Case Report Dermatologic Agents - adverse effects Disability Evaluation Edema - chemically induced Edema - pathology Etodolac - therapeutic use Humans Iatrogenic Disease - prevention & control Isotretinoin - adverse effects Low Back Pain - chemically induced Low Back Pain - pathology Low Back Pain - physiopathology Magnetic Resonance Imaging Male Medicine Medicine & Public Health Muscle Weakness - etiology Muscle Weakness - physiopathology Radiography Rheumatology Sacroiliac Joint - diagnostic imaging Sacroiliac Joint - drug effects Sacroiliac Joint - pathology Treatment Outcome Whole Body Imaging - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We report a case of acute sacroiliitis with severe disability after only 3 weeks of isotretinoin therapy with graduate reduction of pain, limitation and muscle incompetence after discontinuation of the drug and ACTH-depo injection and Ethodolac therapy. Naranjo probability scale indicated a probable relationship between isotretinoin therapy and bilateral sacroiliitis. We discussed possible mechanisms of sacroiliitis and disability due to isotretinoin treatment.
ISSN:	0172-8172 1437-160X
DOI:	10.1007/s00296-009-1014-4