Phytochemical analysis and antibacterial activity of Vitex agnus-castus
The leaves of Vitex agnus-castus was sequentially extracted in hexane, ethyl acetate, methanol and aqueous medium and studied for in vitro antibacterial property. The ethyl acetate extract was found to be most active against all the bacterial species tested except K. pneumoniae. The best MIC value (...
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| Veröffentlicht in: | International journal of green pharmacy 2009-04, Vol.3 (2), p.162 |
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| creator | Arokiyaraj, S Perinbam, K Agastian, P Kumar, RMohan |
| description | The leaves of Vitex agnus-castus was sequentially extracted in hexane, ethyl acetate, methanol and aqueous medium and studied for in vitro antibacterial property. The ethyl acetate extract was found to be most active against all the bacterial species tested except K. pneumoniae. The best MIC value (0.312 mg/ml) was seen against MRSA. Active ethyl acetate extract was further studied for HPTLC fingerprint and phytochemical analysis. HPTLC analysis confirmed segregation of eight individual compounds with individual Rf values and peak area percentage. The results of phytochemical screening of extract revealed the presence of terpenoids, steroids, flavonoids and carbohydrates. This analysis revealed the high antibacterial activity in active ethyl acetate from Vitex agnus- castus. |
| doi_str_mv | 10.4103/0973-8258.54912 |
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The ethyl acetate extract was found to be most active against all the bacterial species tested except K. pneumoniae. The best MIC value (0.312 mg/ml) was seen against MRSA. Active ethyl acetate extract was further studied for HPTLC fingerprint and phytochemical analysis. HPTLC analysis confirmed segregation of eight individual compounds with individual Rf values and peak area percentage. The results of phytochemical screening of extract revealed the presence of terpenoids, steroids, flavonoids and carbohydrates. This analysis revealed the high antibacterial activity in active ethyl acetate from Vitex agnus- castus.</description><identifier>ISSN: 0973-8258</identifier><identifier>EISSN: 1998-4103</identifier><identifier>DOI: 10.4103/0973-8258.54912</identifier><language>eng</language><publisher>Mandsaur: Medknow Publications and Media Pvt. 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The ethyl acetate extract was found to be most active against all the bacterial species tested except K. pneumoniae. The best MIC value (0.312 mg/ml) was seen against MRSA. Active ethyl acetate extract was further studied for HPTLC fingerprint and phytochemical analysis. HPTLC analysis confirmed segregation of eight individual compounds with individual Rf values and peak area percentage. The results of phytochemical screening of extract revealed the presence of terpenoids, steroids, flavonoids and carbohydrates. 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| ispartof | International journal of green pharmacy, 2009-04, Vol.3 (2), p.162 |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Analysis Antibacterial agents Antimicrobial agents Bacteria Bacterial infections Care and treatment Comparative analysis E coli Folk medicine Health aspects Materia medica, Vegetable Metabolites Microbiology Microorganisms Natural products Pharmaceutical industry Phytochemicals Plant extracts Staphylococcus infections Vitex |
| title | Phytochemical analysis and antibacterial activity of Vitex agnus-castus |
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