Examining coding structure and redundancy in DNA

Examining coding structure and redundancy in DNA

A review of DNA signal content, redundancy, and mutational mechanisms is presented. Mutation-robust methods are developed to detect a linear coding structure and approximate tandem repeats. In this article, a method to uncover an error-correction coding structure in the nucleotide sequence is develo...

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Veröffentlicht in:IEEE engineering in medicine and biology magazine 2006-01, Vol.25 (1), p.62-68
1. Verfasser: Rosen, G.
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
DNA
Genetic mutations
Humans
Microsatellites
Protection
Proteins
Redundancy
Sequences
Stability
Uncertainty
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Zusammenfassung:A review of DNA signal content, redundancy, and mutational mechanisms is presented. Mutation-robust methods are developed to detect a linear coding structure and approximate tandem repeats. In this article, a method to uncover an error-correction coding structure in the nucleotide sequence is developed and its efficiency in detecting approximate tandem repeats, such as microsatellite regions, is demonstrated.
ISSN:0739-5175
1937-4186
DOI:10.1109/MEMB.2006.1578665