The role of sterile filtration in the biopharm industry

The role of sterile filtration in the biopharm industry

Again, unspecific adsorption, which is often neglected, should be tested very early in the drug development process to understand which filter membrane polymer is optimal for a particular fluid or application. Yields are very much influenced by unspecific adsorption and can vary greatly between memb...

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Veröffentlicht in:Pharmaceutical technology Europe 2011-01, Vol.23 (1), p.37
1. Verfasser: Jornitz, Maik W
Format: Artikel
Sprache:eng
Schlagworte:
Adsorption
Biological products industry
Biotechnology industry
Filters
Manufacturing
Methods
Organisms
Performance evaluation
Pharmaceutical industry
Pore size
Product quality
Production processes
Sterilization
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Zusammenfassung:Again, unspecific adsorption, which is often neglected, should be tested very early in the drug development process to understand which filter membrane polymer is optimal for a particular fluid or application. Yields are very much influenced by unspecific adsorption and can vary greatly between membrane polymers. Total throughput - the volume that can be filtered through a specified filter device - also has an influence on yield.
ISSN:1753-7967