Modulatory influence of rarely repeated immobilization episodes on the interleukin-1[beta]-dependent reaction of blood leukocytes and hepatoprotective effect of restraint stress

Modulatory influence of rarely repeated immobilization episodes on the interleukin-1[beta]-dependent reaction of blood leukocytes and hepatoprotective effect of restraint stress

Repeated episodes of 1-h restraint stress were accompanied by a decrease in the sensitivity of blood leukocytes and cytochrome P450-dependent monooxygenases of the liver to recombinant IL-[beta]. These changes are associated with the anti-inflammatory hepatoprotective effect of chronic stress. Key W...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2011-02, Vol.150 (4), p.409
Hauptverfasser: Tseilikman, O.B, Tseilikman, V.E, Linin, A.V, Gubkin, D.A, Rudina, E.A, Trubetskoy, S.A, Ivanov, P.V, Pozdnyakov, E.A
Format: Artikel
Sprache:eng
Schlagworte:
Interleukins
Stress (Psychology)
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Zusammenfassung:Repeated episodes of 1-h restraint stress were accompanied by a decrease in the sensitivity of blood leukocytes and cytochrome P450-dependent monooxygenases of the liver to recombinant IL-[beta]. These changes are associated with the anti-inflammatory hepatoprotective effect of chronic stress. Key Words: stress; interleukin-1[beta]; leukocytes; cytochrome P450
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1154-x