A study on strategies for improving growth and body composition after renal transplantation

Allograft function and metabolic effects of four treatment regimens, namely, methylprednisone (MP) standard dose (MP-STD), deflazacort (DFZ), MP-late steroid withdrawal (MP-LSW), and MP-very low dose (MP-VLD), were evaluated in prepubertal patients. MP was decreased by month 4 post-transplantation t...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2010-04, Vol.25 (4), p.753-762
Hauptverfasser:	Ferraris, Jorge R., Pasqualini, Titania, Alonso, Guillermo, Legal, Susana, Sorroche, Patricia, Galich, Ana, Coccia, Paula, Ghezzi, Lidia, Ferraris, Verónica, Karabatas, Liliana, Guida, Clara, Jasper, Héctor
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Blood cholesterol Body composition Body Composition - physiology Bone density Bone Density - drug effects Bone Density - physiology Bones Child Child, Preschool Cholesterol Density Dose-Response Relationship, Drug Drug Administration Schedule Female Graft Rejection - chemically induced Growth Growth - physiology Growth Disorders - physiopathology Growth Disorders - prevention & control Growth Disorders - rehabilitation Humans Immunosuppressive Agents - therapeutic use Kidney Transplantation - adverse effects Kidney Transplantation - rehabilitation Kidney transplants Kidneys Lipids Low density lipoprotein Low density lipoproteins Lumbar Vertebrae - drug effects Lumbar Vertebrae - metabolism Male Medicine Medicine & Public Health Methylprednisolone - therapeutic use Nephrology Original Article Pediatrics Physiological aspects Political aspects Postoperative Complications - prevention & control Postoperative Complications - rehabilitation Pregnenediones - therapeutic use Steroids Toxicity Transplantation Urology
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Zusammenfassung:	Allograft function and metabolic effects of four treatment regimens, namely, methylprednisone (MP) standard dose (MP-STD), deflazacort (DFZ), MP-late steroid withdrawal (MP-LSW), and MP-very low dose (MP-VLD), were evaluated in prepubertal patients. MP was decreased by month 4 post-transplantation to 0.2 mg/kg/day in MP-STD and DFZ patients and to
ISSN:	0931-041X 1432-198X
DOI:	10.1007/s00467-010-1458-5