Ionol (BHT) produces superoxide anion
In aqueous medium etiolated wheat seedlings release superoxide anion (O2*-). Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A n...
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| Veröffentlicht in: | Biochemistry (Moscow) 2002-11, Vol.67 (11), p.1271 |
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| container_issue | 11 |
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| container_title | Biochemistry (Moscow) |
| container_volume | 67 |
| creator | Smirnova, E G Lyubimov, Yu I Malinina, T G Lyubimova, E Yu Alexandrushkina, N I Vanyushin, B F Kolesova, G M Yaguzhinsky, L S |
| description | In aqueous medium etiolated wheat seedlings release superoxide anion (O2*-). Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. In contrast to BHT, they reduce O2*- production by the etiolated wheat seedling system. |
| doi_str_mv | 10.1023/A:1021357506703 |
| format | Article |
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Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. 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Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. 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Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. In contrast to BHT, they reduce O2*- production by the etiolated wheat seedling system.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>12495425</pmid><doi>10.1023/A:1021357506703</doi></addata></record> |
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| subjects | Antioxidants - pharmacology Butylated Hydroxytoluene - chemistry Butylated Hydroxytoluene - pharmacology Kinetics Oxidants - pharmacology Oxygen - chemistry Placenta - chemistry Seeds - drug effects Seeds - metabolism Superoxide Dismutase - pharmacology Superoxides - metabolism Triticum - drug effects Triticum - metabolism Water - chemistry |
| title | Ionol (BHT) produces superoxide anion |
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