Long-Term Antibiotic Use Benefits Patients with Crohn Disease

A study about the benefits of long-term antibiotic use to patients with Crohn disease is presented. The authors conclude that patients with Crohn disease receive substantial benefit from three or more months of therapy with nitroimidazoles and dofazimine. The authors found one trial that supported ciprofloxacin use. Little evidence of benefit was found for clarithromycin or classic antituberculosis drugs.