The nuclear glutathione and its functions

During recent years the nuclear localization of glutathione has been confirmed and this fraction has been quantitatively determined. The nuclear GSH and the enzymes of its metabolism realize independent and important functions. They considerably differ from functions of hyaloplasmic and mitochondria...

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Veröffentlicht in:	Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry Biomedical chemistry, 2010-09, Vol.4 (3), p.224-227
Hauptverfasser:	Kulinsky, V. I., Kolesnichenko, L. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Bioorganic Chemistry Cellular biology Chemistry Chemistry and Materials Science Enzymes Medicinal Chemistry Peptides Reviews Signal transduction
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	During recent years the nuclear localization of glutathione has been confirmed and this fraction has been quantitatively determined. The nuclear GSH and the enzymes of its metabolism realize independent and important functions. They considerably differ from functions of hyaloplasmic and mitochondrial GSH. Glutathione interacts with regulatory pathways, involved into signal transmission into the nucleus.
ISSN:	1990-7508 1990-7516
DOI:	10.1134/S1990750810030029