Decreased Circulating Progenitor Cell Number and Failed Mechanisms of Stromal Cell-Derived Factor-1[alpha] Mediated Bone Marrow Mobilization Impair Diabetic Tissue Repair

Progenitor cells (PCs) contribute to postnatal neovascularization and tissue repair. Here, we explore the mechanism contributing to decreased diabetic circulating PC number and propose a novel treatment to restore circulating PC number, peripheral neovascularization, and tissue healing. Cutaneous wo...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2010-08, Vol.59 (8), p.1974
Hauptverfasser:	Tepper, Oren M, Carr, Jacquelyn, Allen, Ruben J, Chang, Christopher C, Lin, Clarence D, Tanaka, Rica, Gupta, Sanjeev M, Levine, Jamie P, Saadeh, Pierre B, Warren, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Blood vessels Bone marrow Diabetes Flow cytometry Ischemia Research design Wound healing
Online-Zugang:	Volltext
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