Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes

In this randomized trial, sensor-augmented pump therapy was compared with a regimen of multiple daily insulin injections in adults and children with inadequately controlled type 1 diabetes. Pump therapy was associated with a significant improvement in glycated hemoglobin levels, as compared with injection therapy. Improved glycemic control can reduce the microvascular and macrovascular complications associated with type 1 diabetes mellitus, 1 – 3 and diabetes practitioners are continuously challenged to optimize glucose control while minimizing severe hypoglycemia and weight gain. Insulin pumps and systems for continuous glucose monitoring represent technologies designed to assist patients with type 1 diabetes in safely reaching glycemic goals. Among adults, the use of an insulin pump has been shown to reduce glycated hemoglobin levels without an increased risk of hypoglycemia, as compared with a regimen of multiple daily insulin injections, but results in children have been inconsistent. 4 Recent studies have suggested . . .