Important issues in the drug treatment of schizophrenia

The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders...

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Veröffentlicht in:	Schizophrenia bulletin 1980, Vol.6 (1), p.70-87
Hauptverfasser:	Davis, J M, Schaffer, C B, Killian, G A, Kinard, C, Chan, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antipsychotic Agents - adverse effects Antipsychotic Agents - therapeutic use Client Characteristics Dose-Response Relationship, Drug Drug Dosages Drug Therapy Follow-Up Studies Human Humans Literature Review Neuroleptic Drugs Phenothiazines Psychiatric Status Rating Scales Psychotherapy Recurrence Relapse (Disorders) Schizophrenia Schizophrenia - drug therapy Schizophrenic Psychology
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Beschreibung
Zusammenfassung:	The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders; indications for high dosage phenothiazine treatment; indications for maintenance therapy; benefits and risks of antipsychotic drugs. Recommendations are made concerning areas of psychopharmacologic research that require further development.
ISSN:	0586-7614 1745-1701
DOI:	10.1093/schbul/6.1.70