On the relation of thyroid disturbances to maze performance

Previous studies have shown certain interrelations between maze learning, activity, and metabolism. In the present study metabolism was artificially manipulated by thyroidectomy and thyroid feeding. Comparing the maze learning of thyroidectomized, normal, and thyroidfed normal animals it was found that thyroidectomy increases errors and time and reduces retention, while thyroid feeding decreases errors and time. However, the error differences, although in the right direction, were not statistically reliable.