Primary hypertension at a single center: treatment, time to control, and extended follow-up

We present data on presentation, treatment, and follow-up of 65 pediatric patients with primary hypertension treated over the past 12 years, including initial anthropometric data, pharmacologic treatment, time to control for both systolic and diastolic blood pressure (SBP/DBP), and maintenance of co...

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Veröffentlicht in:Pediatric nephrology (Berlin, West) West), 2009-12, Vol.24 (12), p.2421-2428
Hauptverfasser: DiPietro, Amy, Kees-Folts, Deborah, DesHarnais, Susan, Camacho, Fabian, Wassner, Steven Joel
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Sprache:eng
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Zusammenfassung:We present data on presentation, treatment, and follow-up of 65 pediatric patients with primary hypertension treated over the past 12 years, including initial anthropometric data, pharmacologic treatment, time to control for both systolic and diastolic blood pressure (SBP/DBP), and maintenance of control over time. Data was normalized to standard deviation scores (SDS) for mathematical analysis, and antihypertensive medication dosages were converted to dosage equivalents for a single member of each antihypertensive class. We used multiple regression analysis and Kaplan-Meier survival curves to determine the time to control, medication, and dose effectiveness. Patients were seen for an average of seven visits over 25 months. Initial BPs averaged 134/71 mmHg (2.1/0.6 SDS). Patients were taller, heavier, and had higher body mass index than average for age and sex. By the fourth visit, SBP was
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-009-1297-4