Intraoperative FiO 2 and risk of impaired postoperative oxygenation in lung resection: A propensity score-weighted analysis

To assess whether, in a lung resection cohort with a low probability of confounding by indication, higher FiO is associated with an increased risk of impaired postoperative oxygenation - a clinical manifestation of lung injury/dysfunction. Pre-specified registry-based retrospective cohort study. Two...

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Veröffentlicht in:Journal of clinical anesthesia 2025-02, Vol.101, p.111739
Hauptverfasser: Choi, Alex, Deng, Hao, Fuller, Mitchell, Sparling, Jamie L, Zhu, Min, Udelsman, Brooks, Frendl, Gyorgy, Vidal Melo, Marcos F, Nagrebetsky, Alexander
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Sprache:eng
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Zusammenfassung:To assess whether, in a lung resection cohort with a low probability of confounding by indication, higher FiO is associated with an increased risk of impaired postoperative oxygenation - a clinical manifestation of lung injury/dysfunction. Pre-specified registry-based retrospective cohort study. Two large academic hospitals in the United States. 2936 lung resection patients with an overall good intraoperative oxygenation (median intraoperative SpO  ≥ 95 %). We compared patients with a higher (≥0.8) and lower (
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2024.111739