Chiral Secondary Phosphine Oxide Ligands in Asymmetric Ni−Al Bimetallic Catalysis

Ligands play a key role in asymmetric transition‐metal catalysis. Among reported chiral ligands, readily available and air‐stable secondary phosphine oxide ligands are unique and have aroused wide interest in Ni−Al bimetallic catalysis, since they can act as bifunctional ligands to ligate two metals for stronger bimetallic synergism, greatly enhancing reactivity and selectivity. Hence, in this mini review we will focus on secondary phosphine oxides and their applications in asymmetric Ni−Al bimetallic catalysis. Ligands play a key role in asymmetric transition‐metal catalysis. Among reported chiral ligands, readily available and air‐stable phosphine oxide ligands are unique and have aroused wide interest, especially in Ni−Al bimetallic catalysis, since they can act as bifunctional ligands to ligate two metals for stronger bimetallic synergism, greatly enhancing reactivity and selectivity. Hence, in this mini review we will focus on phosphine oxides and their applications in asymmetric Ni−Al bimetallic catalysis.