Network pharmacology approach to understand Kodo millet cardioprotective activity

Kodo millet, commonly referred to as "Varagu" or "Kodra" is a kind of millet that plays an important role in the Ayurveda nutritional concept. According to Ayurveda, nutrition is essential for sustaining health and preventing disease. Because of its nutritional richness and potential health benefits, Kodo millet has been used in Ayurveda since ancient times. However, the network's pharmacology technique greatly aids in understanding the scientific use of any herb. Network pharmacology is an interdisciplinary approach to understanding how drugs act within intricate biological networks, such as signaling pathways, protein-protein interactions, and metabolic pathways. It studies the interactions between drugs, their targets, and biological systems. This study explores the possibility of using network pharmacology to comprehend the rationale behind the use of Kodo millet. Based on data obtained from various sources, pharmacology networks for Kodo millet were constructed. The paper illustrates how bioactives interact with molecular targets and how this affects diseases, particularly cardiovascular disorders.