Naturstoffe aus der Vergangenheit

Naturstoffe aus der Vergangenheit

Low molecular weight compounds biosynthesized by microorganisms, commonly known as natural products, are indispensable in modern medicine. They serve as the basis for many antibiotics, immunomodulators, and anti cancer agents. The new research field of paleobiotechnology allows access to natural pro...

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Veröffentlicht in:Biospektrum 2024-11, Vol.30 (7), p.744-746
Hauptverfasser: Klapper, Martin, Ramm, Michael, Stallforth, Pierre
Format: Artikel
Sprache:ger
Schlagworte:
Antibiotics
Antineoplastic drugs
Biochemistry
Biomedical and Life Sciences
Dental calculus
Human Genetics
Immunomodulation
Life Sciences
Microbiology
Molecular weight
Natural products
Pharmacology/Toxicology
Wissenschaft
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Zusammenfassung:Low molecular weight compounds biosynthesized by microorganisms, commonly known as natural products, are indispensable in modern medicine. They serve as the basis for many antibiotics, immunomodulators, and anti cancer agents. The new research field of paleobiotechnology allows access to natural products of the past. Based on ancient DNA from dental calculus, it was possible to generate bacterial natural products dating back over 100,000 years.
ISSN:0947-0867
1868-6249
DOI:10.1007/s12268-024-2339-y