Acylation of Azepanoglycyrrhetol

Acylation of Azepanoglycyrrhetol

Acylation of azepano-11-deoxoglycyrrhetol synthesized N -acetyl- and N,O -bis-acetyl derivatives. The structure of azepano-11-deoxoglycyrrhetol was confirmed by an XSA. Data for its influence on cell cycle progression suggested that suppression of cell survival was due primarily to a cytostatic effe...

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Veröffentlicht in:Chemistry of natural compounds 2024-11, Vol.60 (6), p.1066-1071
Hauptverfasser: Terekhova, A. V., Petrova, A. V., Kazakova, O. B., Vakhitova, Yu.V., Polovyanenko, D. N., Bagryanskaya, I. Yu
Format: Artikel
Sprache:eng
Schlagworte:
Acylation
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Organic Chemistry
Plant Sciences
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Zusammenfassung:Acylation of azepano-11-deoxoglycyrrhetol synthesized N -acetyl- and N,O -bis-acetyl derivatives. The structure of azepano-11-deoxoglycyrrhetol was confirmed by an XSA. Data for its influence on cell cycle progression suggested that suppression of cell survival was due primarily to a cytostatic effect that was related to arrest of the S or G1 phase, depending on the cell line.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-024-04521-1