Hybrid Paper/Polyester‐Based Laser‐Induced Graphene Electrodes for Electrochemical Detection of Tadalafil

Here, we describe for the first time the fabrication of laser‐induced graphene (LIG) electrodes on a hybrid substrate composed of sandpaper and polyester. As a proof of concept, the proposed device was used as a voltammetric sensor for tadalafil (TAD) quantification in authentic tablet samples. The electrochemical TAD sensing based on differential pulse voltammetry (DPV) revealed a linear behavior in the concentration range from 25 to 250 μmol L−1(R2=0.99), a limit of detection of ~9.6 μmol L−1, sensitivity of ~0.0048 μA(μmol L−1)−1 and acceptable reproducibility values (RSD≤5.8 %). The DPV responses involving the standard addition method in pharmaceutical samples presented recovery results of TAD ranging from 93 to 108 %. Also, the proposed analytical method offered a suitable green analytical chemistry profile. We successfully demonstrated the fabrication of graphene‐like sites and nanoparticles composed of alumina upon a hybrid substrate. Laser‐induced graphene (LIG) electrodes was created on a hybrid substrate. The explored hybrid material was composed of sandpaper and polyester. Carbonized material exhibited non‐oriented porous structures like popcorn anchored with alumina nanoparticles oxide. The LIG device was used as a voltammetric sensor for tadalafil quantification in authentic tablet samples.