Antibacterial activity of methanolic extract from the plant of Sapium insigne against human pathogens

The objective of this study was to determine whether or not a methanolic extract of Sapium insigne possessed any antibacterial properties when applied to dangerous bacteria that had been extracted from human participants for the purpose of medical treatment. An approach that is methodical and involv...

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Hauptverfasser: Harshitha, Seedevi, P.
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:The objective of this study was to determine whether or not a methanolic extract of Sapium insigne possessed any antibacterial properties when applied to dangerous bacteria that had been extracted from human participants for the purpose of medical treatment. An approach that is methodical and involves careful preparation: Through the use of the agar well diffusion method, the antibacterial activity of the methanolic extract was evaluated against 10 human pathogenic pathogens. This study utilised dosages with concentrations ranging from 25 to 100 µg/ml for the purpose of the investigation. It was discovered that the inhibitory zone for Group 2, Group 4, Group 5, and Group 6 was around 50 µg/ml, 75 µg/ml, 100 µg/ml, and 100 µg/ml, respectively. The fifth group served as the study’s control group. a control that is opposite. In order to determine the appropriate sample size, we utilised a pre-test G power of eighty percent. The results of the methanolic extract were positive because it was able to reduce the number of viable cells in eight out of ten clinical bacterial strains. When the maximal effective dose of 100 µg/ml was administered, the methanolic extract exhibited an inhibitory zone measuring 20mm against S. typhi pathogen. A significance criterion of p
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0233368