Reaction of 5-Hydroxypyrazolidine with Thiol-Containing Hydrazides as a Route to Biologically Active Ligands for Gold Glyconanoparticles

The reaction of (3S)-1-acetyl- 5-hydroxy-2-phenyl-3-methylpyrazolidine with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides gives in 60–65% yields (3 S )-1-acetyl-5-[(ω -mercaptoacyl)hydrazino]-2-phenyl-3-methylpyrazolidines, promising coligands for preparing gold glyconanoparticles for...

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Veröffentlicht in:Russian journal of organic chemistry 2024-07, Vol.60 (7), p.1348-1350
Hauptverfasser: Ershov, A. Yu, Martynenkov, A. A., Lagoda, I. V., Batyrenko, A. A.
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container_issue 7
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container_title Russian journal of organic chemistry
container_volume 60
creator Ershov, A. Yu
Martynenkov, A. A.
Lagoda, I. V.
Batyrenko, A. A.
description The reaction of (3S)-1-acetyl- 5-hydroxy-2-phenyl-3-methylpyrazolidine with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides gives in 60–65% yields (3 S )-1-acetyl-5-[(ω -mercaptoacyl)hydrazino]-2-phenyl-3-methylpyrazolidines, promising coligands for preparing gold glyconanoparticles for the biomedical purpose.
doi_str_mv 10.1134/S1070428024070273
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subjects Chemistry
Chemistry and Materials Science
Gold
Hydrazides
Organic Chemistry
title Reaction of 5-Hydroxypyrazolidine with Thiol-Containing Hydrazides as a Route to Biologically Active Ligands for Gold Glyconanoparticles
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