Ab. No. 105 A Scoping Review of the Effectiveness of Various Exercise Regimens on the Severity of Uremic Restless Leg Syndrome and Other Outcome Metric in Hemodialysis Subjects

Introduction:Uremic restless leg syndrome (URLS) is a condition that occurs in individuals with kidney failure or severe kidney disease;characterized by an uncontrollable urge to move the legs, often accompanied by discomfort or a crawling sensation.URLS can be prevalent in hemodialysis patients, as kidney dysfunction contributes to its development. Hemodialysis helps in removing waste products from the blood, but it may not completely alleviate URLS symptoms. The purpose of this scoping review is to outline the literature on physiotherapy in URLS, the types of physiotherapy interventions used and the outcome measures used.Methods:Scoping review in accordance with Joanna Briggs Institute guidelines. From 2005 to December 2023, databases searched included PubMed, PEDro, Research Gate and Google Scholar following MESH terminology and boolean operators in accordance to the study requirement.A narrative data summary was created to explain the current evidence on physiotherapy for URLS. Articles were considered if they were about physiotherapy interventions given to URLS subjects. A narrative synthesis was conducted.Results:Ten studies were included (eight randomised control trials, one pilot RCTs, one quasi experimental study). PEDro scale for 4 studies were ≥5 and 6 studies were ≥5.Interventions reported were aerobic,resistance and stretching exercise. A variety of outcome measures was utilised such as severity of URLS, physical performance, balance, sleep quality, depression score and quality of life domains.Conclusion:The results of this review suggest that there is insufficient information to assist physiotherapists in the treatment of subjects with URLS. Aerobic, resistance and stretching exercise were the widely studied physiotherapy therapies. A variety of outcome metrics are used. High-quality clinical trials with representative populations are needed, as are investigations on physiotherapy practice and the experiences of subjects with URLS.