1486-P: Role of HLA Class I Gene Alleles and Haplotypes in Type 1 Diabetes in Kuwaiti Children

Introduction & Objective: HLA class I genes have a role in influencing immune response and self-tolerance as they bind and present antigens to T cells. Allelic variations of these genes are associated with multifactorial autoimmune conditions including type 1 diabetes (T1D) and show variability...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73 (Supplement_1), p.1
Hauptverfasser:	DASHTI, MOHAMMED H., ZUBBAIR MALIK, MD, NIZAM, RASHEEBA, JACOB, SINDHU, ALKANDARI, HESSA, ALOZAIRI, EBAA S., THANGAVEL, ALPHONSE T., ALMULLA, FAHD
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino acids Autoantigens Diabetes Diabetes mellitus (insulin dependent) Genetic counseling Genetic diversity Haplotypes Histocompatibility antigen HLA Immunogenicity Immunological tolerance Lymphocytes T Minority & ethnic groups Next-generation sequencing Population genetics
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