970-P: Safety and Glucose Control with "Do It Yourself Android Artificial Pancreas System" Using Freestyle Libre Sensor + MiaoMiao in Patients with Type 1 Diabetes

Introduction & Objective: Do it yourself (DIY) Android Artificial Pancreas Systems (AAPS) integrate insulin infusion and glucose sensors at lower cost than commercial systems. Freestyle Libre™ 1 + MiaoMiao™ + insulin pump has been poorly studied for this purpose. This study aims to evaluate the effectiveness and safety of this system in patients with type 1 diabetes (T1D). Methods: This is an observational study performed in Brazil. Patients were recruited through social media. Data was collected remotely with a questionnaire (AirTable). Non pregnant individuals with more than 3 years of T1D who used DIY AAPS were included. Continuous glucose monitoring data, quality of life (QOL) through DQOL-Brazil instrument and hemoglobin A1c (A1c) prior and after treatment were accessed. Results: 69 patients were included, with mean age and disease duration of 36.4 ± 13.2 and 20.9 ±12.1 years, respectively. Among them, 60.9% had higher education. Mean time in range, hypoglycemia < 70 mg/dL, hypoglycemia < 54 mg/dL, hyperglycemia > 180 mg/dL, hyperglycemia > 250 mg/dL and glucose coefficient variability were 78.5% ± 16.6, 4.1% ± 3.4, 1.3% ± 1.8, 16.1% ± 11.9, 4.1% ± 5.6 and 46.3% ±16.2, respectively. Mean A1c before and after treatment were 8.9 ± 11.6 and 6.4% ± 0.7, respectively. 75.5% of patients had A1c