1195-P: Remote Self-Monitoring of Blood Glucose (SMBG) in Youth with Preclinical Type 1 Diabetes (T1D)

Introduction & Objective: Screening for preclinical T1D and early-stage monitoring are typically only accessible in research studies, but will likely soon expand to clinical settings. Potential strategies for conducting monitoring of early-stage T1D in clinical settings must be explored. This study assessed feasibility of remote SMBG in youth with preclinical T1D. Methods: Participants from the Autoimmunity Screening for Kids (ASK) study were eligible if enrolled in ASK ≥6 months prior to this study's start. Upon enrollment in the SMBG study, participants transitioned to an advanced technology glucometer (OneTouch Verio Reflect®) with remote data sharing capability. 12 months of remotely transferred SMBG data was collapsed into 3-month sums and SMBG frequency was explored with Poisson regression. Results: Data from 42 participants were included (age 13 ± 4.1 years, 62% non-Hispanic white, 62% female, 17% T1D first-degree relative). Frequency of SMBG was highest in the first 3 months (median [IQR]: 3.0 [1.0-8.5]). SMBG frequency decreased over time; there were fewer SMBG in months 4-6 (1.0 [0.0-4.3]), 7-9 (0.0 [0.0-2.3]), and 10-12 (0.0 [0.0-2.0]) (p