1231-P: Decreased Complexity of Glucose Time Series Index Associated with Adverse Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus—A Retrospective Cohort Study

1231-P: Decreased Complexity of Glucose Time Series Index Associated with Adverse Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus—A Retrospective Cohort Study

Introduction & Objective: According to previous researches, the complexity of glucose time series index (CGI) may be a new indicator of glucose homeostasis. We aimed to investigate the relationship between the CGI during pregnancy and adverse pregnancy outcomes in gestational diabetes mellitus (...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73 (Supplement_1), p.1
Hauptverfasser: LIANG, GUILING, LAI, MENGYU, WANG, YAXIN, LU, JINGYI, ZHOU, JIAN, WANG, YUFAN
Format: Artikel
Sprache:eng
Schlagworte:
Cohort analysis
Diabetes mellitus
Gestational age
Gestational diabetes
Glucose
Glucose monitoring
Homeostasis
Pregnancy
Pregnancy complications
Time series
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Zusammenfassung:Introduction & Objective: According to previous researches, the complexity of glucose time series index (CGI) may be a new indicator of glucose homeostasis. We aimed to investigate the relationship between the CGI during pregnancy and adverse pregnancy outcomes in gestational diabetes mellitus (GDM) patients. Methods: In this retrospective cohort study, a total of 388 singleton-pregnant patients with GDM were recruited and underwent continuous glucose monitoring (CGM) at a median of 26.86 gestational weeks. The CGI was measured with refined composite multiscale entropy based on CGM data. Participants were categorized into tertiles according to CGI at baseline (CGI
ISSN:0012-1797
1939-327X
DOI:10.2337/db24-1231-P