An Engineered Anisotropic Skeletal Muscle Organoid‐on‐a‐Chip for Deciphering Muscle Response under Intermittent Hypoxia (Adv. Funct. Mater. 39/2024)

Organoid‐on‐a‐Chip In article number 2401564, Tingjiao Liu, Yuehua Liu, and co‐workers develop a novel approach to construct a functional skeletal muscle organoid‐on‐a‐chip, yielding highly organized muscle structures and contractile functionality. This research unveils the adaptive and decompensatory responses of skeletal muscle to various intermittent hypoxia conditions and serves as a reliable platform for drug screening, highlighting its potential in disease modeling and regenerative therapies.