Bio-analytical method development and validation of dichlorvos pesticide by rp-uflc method
Organophosphates are a group of pesticides that were developed in the 1940s in Germany andsoon became a sig nificant defense against agricultural pests. The organophosphate Dichlorvos is a commonly used group of pesticide is a broad-spectrum organophosphate compound having insecticidal activity. Dic...
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| Veröffentlicht in: | Research journal of pharmacy and technology 2020-08, Vol.13 (8), p.3725-3728 |
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| container_title | Research journal of pharmacy and technology |
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| creator | Lal, C. L Vaishnav Chandan, R. S Maruthi, R Tengli, Anand Kumar |
| description | Organophosphates are a group of pesticides that were developed in the 1940s in Germany andsoon became a sig nificant defense against agricultural pests. The organophosphate Dichlorvos is a commonly used group of pesticide is a broad-spectrum organophosphate compound having insecticidal activity. Dichlorvos is a cholinesterase inhibitor exhibiting stomach, contact and systemic mode of action. The development of bioanalytical method is the process of developing a procedure for the detection and quantification of a compound of interest in a biological fluid. A simple, reliable, fast, accurate and economical RP-UFLC method have been developed and validated for quantitative determination of Dichlorvos. The RP-UFLC procedure is developed by using ACN and Millipore water 50:50 v/v as mobile phase, Flow rate is maintained at 1.5mL/minute. Detection of Dichlorvos was performed by using PDA detector at 200nm. By this RP-UFLC procedure retention time (RT) of Dichlorvos was identified at 2.9 min. |
| doi_str_mv | 10.5958/0974-360X.2020.00659.9 |
| format | Article |
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The RP-UFLC procedure is developed by using ACN and Millipore water 50:50 v/v as mobile phase, Flow rate is maintained at 1.5mL/minute. Detection of Dichlorvos was performed by using PDA detector at 200nm. 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A simple, reliable, fast, accurate and economical RP-UFLC method have been developed and validated for quantitative determination of Dichlorvos. The RP-UFLC procedure is developed by using ACN and Millipore water 50:50 v/v as mobile phase, Flow rate is maintained at 1.5mL/minute. Detection of Dichlorvos was performed by using PDA detector at 200nm. 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| subjects | Accuracy Calibration Chemicals Chromatography Conflicts of interest Insecticides Pesticides Poisoning Sensors Toxicity Toxicology |
| title | Bio-analytical method development and validation of dichlorvos pesticide by rp-uflc method |
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