Multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis

Multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis

We design a multi-effective nanoplatform (CeO 2 :Nd@SiO 2 @CeO 2 :Yb,Er@SiO 2 -RB/MB/CD36) with down/upconversion dual-mode emissions and targeting ability in foam macrophages. Under NIR excitation, this nanoplatform can realize in vivo NIR-II imaging and PDT/PTT coordinated therapy for early AS sim...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2024-09, Vol.6 (75), p.1386-1389
Hauptverfasser: Gao, Wen, Lv, Lijun, Li, Guanghan, Zhao, Hongxiu, Zhou, Jia, Cheng, Yuan, Tang, Bo
Format: Artikel
Sprache:eng
Schlagworte:
Atherosclerosis
Cerium oxides
Erbium
Macrophages
Silicon dioxide
Upconversion
Ytterbium
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Zusammenfassung:We design a multi-effective nanoplatform (CeO 2 :Nd@SiO 2 @CeO 2 :Yb,Er@SiO 2 -RB/MB/CD36) with down/upconversion dual-mode emissions and targeting ability in foam macrophages. Under NIR excitation, this nanoplatform can realize in vivo NIR-II imaging and PDT/PTT coordinated therapy for early AS simultaneously. We design a multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis.
ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d4cc03538k