Electrical Stimulation of Human Dermal Fibroblasts on Conducting Matrix

Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials (±100 mV) were studied; the scaffold demo...

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Veröffentlicht in:Technical physics 2024, Vol.69 (3), p.578-585
Hauptverfasser: Kolbe, K. A., Shishov, M. A., Sapurina, I. Yu, Smirnova, N. V., Kodolova-Chukhontseva, V. V., Dresvyanina, E. N., Kamalov, A. M., Yudin, V. E.
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Sprache:eng
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Zusammenfassung:Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials (±100 mV) were studied; the scaffold demonstrated high stability in the course of prolonged electric cycling. It was shown that preliminary electrical stimulation facilitated proliferative activity of human dermal fibroblasts in comparison to that of intact cells.
ISSN:1063-7842
1090-6525
DOI:10.1134/S1063784224020166