144-OR: A Randomized Clinical Trial of Automated Insulin Delivery in Elderly with Type 1 Diabetes

144-OR: A Randomized Clinical Trial of Automated Insulin Delivery in Elderly with Type 1 Diabetes

Background: Older adults with T1D are a growing population at risk for severe hypoglycemia. Automated insulin delivery (AID) approaches that can reduce risk have not been sufficiently evaluated in this population. Methods: We conducted a multicenter, randomized, crossover trial in adults ≥65 years w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73, p.1
Hauptverfasser: Kudva, Yogish C, Henderson, Robert, Kanapka, Lauren, Weinstock, Ruth S, Rickels, Michael R, Pratley, Richard E, Chaytor, Naomi, Janess, Kamille, Desjardins, Donna, Pattan, Vishwanath, Peleckis, Amy, Casu, Anna, Rizvi, Shafaq Raza, Bzdick, Suzan, Whitaker, Keri J, Kamimoto, Jorge L JO, Miller, Kellee, Beck, Roy
Format: Artikel
Sprache:eng
Schlagworte:
Automation
Diabetes
Diabetes mellitus (insulin dependent)
Hyperglycemia
Hypoglycemia
Insulin
Intelligence
Older people
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background: Older adults with T1D are a growing population at risk for severe hypoglycemia. Automated insulin delivery (AID) approaches that can reduce risk have not been sufficiently evaluated in this population. Methods: We conducted a multicenter, randomized, crossover trial in adults ≥65 years with T1D experiencing hypoglycemia (>1.5% time < 70 mg/dL based on CGM). Participants completed 3 sequential 12-week periods of hybrid-closed (HCL) loop with Tandem Control-IQ technology, predictive low glucose suspend (PLGS) with Tandem Basal-IQ technology, and sensor augmented pump (SAP) insulin delivery. The primary outcome was % time
ISSN:0012-1797
1939-327X
DOI:10.2337/db24-144-OR