1909-LB: Patient Preferences for Continuous Glucose Monitoring Devices-A Discrete Choice Experiment Study of People Living with Type 2 Diabetes

Introduction & Objective: While continuous glucose monitoring (CGM) devices have received approval for use in eligible patients, there remains limited evidence regarding patient preferences for these devices. This study aims to determine the important attributes of CGM devices for patients with type 2 diabetes (T2D).Methods: A cross-sectional, web-based, discrete choice experiment (DCE) survey was conducted. Seven attributes of CGM devices, including the approach to access data, alarm function, information on receiver screen (including measurement frequency and prediction arrow), accuracy, calibration frequency, sensor lifespan, and out-of-pocket cost, were identified through a literature review and consultation with five clinical experts. A D-efficient design was used to generate DCE choice sets. Data were collected from 242 American adults living with T2D who were proficient in English. A mixed logit model was used to determine the preference weights of all attributes. Conditional relative importance was calculated by differentiating each attribute's highest and lowest level of its preference weights.Results: A total of 182 patients were included in the analysis. The preference weights of all attributes, except the information on receiver screen, were statistically significant and in the expected direction (e.g., patients prefer lower out-of-pock cost). The conditional relative importance of out-of-pocket cost was the greatest (3.19, SE=0.75), followed by accuracy (1.40, SE=0.37), calibration frequency (1.01, SE=0.27), alarm function (0.94, SE=0.27), sensor lifespan (0.60, SE=0.22), and approach to access data (0.26, SE=0.13).Conclusion: While patients with T2D considered various attributes when selecting CGM devices, out-of-pocket cost was their primary concern. Notably, information on receiver screen was not a significant attribute, underscoring the need for further investigation into its implications.