1960-LB: A 3D Analysis of CD8+ Leukocytic Infiltration in Human Endocrine and Exocrine Pancreas at Type 1 Diabetes Onset

Introduction: Elevations in immune cell numbers are well documented in both the endocrine and exocrine pancreas in type 1 diabetes (T1D), with CD8+ T cells representing the predominant cell type in islet inflammation (insulitis). To expand on previous 2D characterizations, we used 3D light sheet flu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73 (Supplement_1), p.1
Hauptverfasser:	RIPPA, ALEXANDRA, DROTAR, DENISE M., POSGAI, AMANDA, HULME, MAIGAN A., WASSERFALL, CLIVE, KUSMARTSEVA, IRINA, CAMPBELL-THOMPSON, MARTHA, ATKINSON, MARK A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies CD8 antigen Diabetes Diabetes mellitus (insulin dependent) Glucagon Infiltration Inflammation Insulitis Lymphocytes T Pancreas
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!