Biochemical Markers and NLR Levels in Covid-19 Infection: In Cases With Severe Pulmonary Involvement According to CT Score

[LANGUAGE= "English"] INTRODUCTION: Many studies have been conducted on ferritin, fibrinogen, D-dimer, and neutrophil-lymphocyte ratio (NLR), which are biochemical tests, to determine the severity and prognosis of the disease in the early period of coronavirus disease 2019 (COVID-19) infec...

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Veröffentlicht in:International Journal of Medical Biochemistry 2023, Vol.6 (1), p.8
Hauptverfasser: Firat, Asuman Akkaya, Kilic, Haluk, Elarslan, Serkan, Yildirim, Gulsah, Kilic, Ebru Tarikci, Ayan, Ugur
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Sprache:eng
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Zusammenfassung:[LANGUAGE= "English"] INTRODUCTION: Many studies have been conducted on ferritin, fibrinogen, D-dimer, and neutrophil-lymphocyte ratio (NLR), which are biochemical tests, to determine the severity and prognosis of the disease in the early period of coronavirus disease 2019 (COVID-19) infection. We aimed to determine the compatibility of these easily accessible and affordable tests with computed tomography (CT) in determining the severity of the disease at an early stage.METHODS: This study was carried out retrospectively on 79 patients. In all patients, nasal and pharyngeal swabs were collected and tested for SARS-CoV-2 RNA with reverse transcription-polymerase chain reaction assay. The severity of the disease was determined by computed tomography imaging. According to lung involvement, patients who were found to have a severe infection and divided into the severe group (n=26), and those with milder symptoms were divided into the non-severe group (n=53). The demographic information and laboratory parameters of the patients were obtained from the medical records of the hospital. Analyses were performed using the Statistical Package for the SocialSciencesversion 23.0 for Windows.RESULTS: NLR (8.36±2.45; 3.3±2.04 p
ISSN:2587-2362
2618-642X
DOI:10.14744/ijmb.2022.14890