Coupling of α-(1H-Benzotriazol-1-yl) Nitrones with Grignard Reagents: Access to Ketonitrones

A new procedure for the synthesis of novel ketonitrones has been developed. The procedure involves the coupling of Grignard reagents with the easily accessible and stable N -substituted α-(1 H -benzotriazol-1-yl) nitrones in the presence of catalytic amounts of zinc bromide.

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Veröffentlicht in:Russian journal of organic chemistry 2024-05, Vol.60 (5), p.950-955
1. Verfasser: Widyan, Khalid
Format: Artikel
Sprache:eng
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Zusammenfassung:A new procedure for the synthesis of novel ketonitrones has been developed. The procedure involves the coupling of Grignard reagents with the easily accessible and stable N -substituted α-(1 H -benzotriazol-1-yl) nitrones in the presence of catalytic amounts of zinc bromide.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428024050178