Recent Advances in Chiral Electrodes for Asymmetric Electrosynthesis

Asymmetric electrosynthesis provides an efficient and controllable route for chiral synthesis. In comparison to traditional symmetric synthesis methods, asymmetric electrosynthesis typically operates under milder conditions, reducing waste generation and energy consumption. This aligns with the current trend in green chemistry, contributing to the development of environmentally friendly synthetic pathways. Apart from reactions initiated with chiral substrates, introducing appropriate chiral factors during the electrochemical process is crucial. In this context, chiral electrodes have garnered significant attention due to their advantages such as high catalytic activity, enantioselectivity, and reusability. This concept aims to introduce the preparation of three main types of chiral electrodes over the past decade, including chiral modified electrodes, chiral immobilized electrodes and chiral imprinted electrodes, and their applications in asymmetric electrosynthesis. The article provides insights into the current state of the field and outlines prospects for future research. Asymmetric synthesis, especially asymmetric electrosynthesis, provides an efficient and controllable route for chiral synthesis. Chiral electrodes have the characteristics of high catalytic activity, stereochemical selectivity, and reusability. The preparation of chiral electrodes over the past decade and their applications in asymmetric electrosynthesis were summarized in this concept.