Molecular engineering of metal-based photosensitizers with narrow band gap for efficient photodynamic therapy

Three iridium( iii ) complexes were designed with the purpose of elucidating the photo-physicochemical properties of iridium( iii ) complexes with narrow band gap at the electronic level. This study indicates that increasing the ligand rigidity and electron delocalization of the compounds can suppress the ring-stretching vibrations of the iridium( iii ) complex, thus improving their photo-chemical activity and photocytotoxicity. Three iridium( iii ) complexes were designed with the purpose of investigating the photo-physicochemical behaviors of iridium( iii ) complexes with narrow band gap for photodynamic therapy.