Thyroid profile in pre-diabetes, is it important?

Background: Individuals with type 2 diabetes mellitus and pre-diabetes have an increased risk of coronary artery disease. Thyroid dysfunction may amplify existing cardiovascular disease risk in hyperglycemic subjects. Studying the association between thyroid profile abnormalities in the pre-diabetes...

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Veröffentlicht in:National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2024, Vol.14 (7), p.1-1475
Hauptverfasser: Mishra, Soumyaranjan, Mohanty, Namita, Nahak, Susanta, Pati, Sandhyarani, Tripathy, Ashutosha
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container_end_page 1475
container_issue 7
container_start_page 1
container_title National journal of physiology, pharmacy and pharmacology
container_volume 14
creator Mishra, Soumyaranjan
Mohanty, Namita
Nahak, Susanta
Pati, Sandhyarani
Tripathy, Ashutosha
description Background: Individuals with type 2 diabetes mellitus and pre-diabetes have an increased risk of coronary artery disease. Thyroid dysfunction may amplify existing cardiovascular disease risk in hyperglycemic subjects. Studying the association between thyroid profile abnormalities in the pre-diabetes population is of considerable clinical importance. Aims and Objectives: The aims and objectives of the study are to study thyroid profile in pre-diabetes and control. Materials and Methods: Group-I: Patients with pre-diabetes are considered cases. (patients with fasting plasma glucose [FPG] – 100–125 mg/dL and/or post-prandial blood glucose 140–199 mg/dL and/or hemoglobin A1c [HbA1c] – 5.7–6.4% as per “American Diabetes Association 2017”). Group-II: Patients with normal FPG, post-prandial blood glucose, and HbA1C are considered controls. Results: Among pre-diabetes, 12% have hypothyroidism as compared to 5% among non-diabetic (P < 0.001). Conclusion: There is a significant increase in the prevalence of hypothyroidism among the prediabetes population. Hence, they should be screened early for these parameters and early management may reduce future cardiovascular morbidity and mortality.
doi_str_mv 10.5455/njppp.2024.14.03124202402062024
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Thyroid dysfunction may amplify existing cardiovascular disease risk in hyperglycemic subjects. Studying the association between thyroid profile abnormalities in the pre-diabetes population is of considerable clinical importance. Aims and Objectives: The aims and objectives of the study are to study thyroid profile in pre-diabetes and control. Materials and Methods: Group-I: Patients with pre-diabetes are considered cases. (patients with fasting plasma glucose [FPG] – 100–125 mg/dL and/or post-prandial blood glucose 140–199 mg/dL and/or hemoglobin A1c [HbA1c] – 5.7–6.4% as per “American Diabetes Association 2017”). Group-II: Patients with normal FPG, post-prandial blood glucose, and HbA1C are considered controls. Results: Among pre-diabetes, 12% have hypothyroidism as compared to 5% among non-diabetic (P &lt; 0.001). Conclusion: There is a significant increase in the prevalence of hypothyroidism among the prediabetes population. 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subjects Blood pressure
Cardiovascular disease
Diabetes
Endocrinology
Glucose
Hemoglobin
Hyperglycemia
Hypothyroidism
Immunoassay
Morbidity
Mortality
Thyroid diseases
title Thyroid profile in pre-diabetes, is it important?
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